① Accelerating Research on Aging Prevention 

Glico demonstrates senescent cell removal by Persian silk tree and obtains patent —Discovered from Glico’s Library of 6,000 Curated Ingredients —

Ezaki Glico Co., Ltd. conducted research to identify ingredients that act on the causes of aging, selecting approximately 6,000 candidates from its curated ingredient library, with a focus on those suitable for food applications. As a result, Glico demonstrated that Persian silk tree removes senescent cells (senolysis*1), and has now obtained a Patent (Patent No. 7659690). This marks the first patent in Japan for the removal of senescent cells using Persian silk tree. Moving forward, the Glico Group will continue its research, including validation in humans, to further explore its potential in aging-related applications. 

For more information, please visit <a href="https://www.glico.com/global/news/46993/">https://www.glico.com/global/news/46993/</a>.

② Each Piece Encapsulates the Gentle Essence of Rice and a Vision for the Future of Our Planet 

Glico develops “Rice soft candy” using rice-derived ingredients To be distributed exclusively inside “EARTH MART” at Expo 2025 Osaka, Kansai from the End of May

Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” at Expo 2025 Osaka, Kansai. Under the pavilion’s theme, “Thinking about the lives through eating”, Glico has developed “Rice soft candy” by applying the soft-candy-making technology it has cultivated since its founding—using rice, Japan’s staple food, as the key ingredient. “Rice soft candy” will be offered free of charge to pavilion visitors exclusively within “EARTH MART”, starting from the End of May. The Glico Group will continue to share the value of Japanese food culture with the world and offer new ideas that contribute to “Healthier days, Wellbeing for life”.

For more information, please visit <a href="https://www.glico.com/global/news/47011">https://www.glico.com/global/news/47011</a>.

*1 Senolysis: Refers to the selective removal of senescent cells. The term is derived from seno (senescence) and lysis (destruction or breakdown).

This document is an English translation of the Japanese original. In the event of any differences or inconsistencies between the Japanese and English versions, the Japanese language version shall take precedence.

Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” and a Premium Partner of the “Osaka Healthcare Pavilion” at Expo 2025 Osaka, Kansai. As part of its participation in both pavilions, Glico held a press briefing on April 30 to share two key announcements: a newly obtained patent related to its “Cellular-care” research, and the development of “Rice soft candy” for the Expo 2025. At the “Osaka Healthcare Pavilion”, Glico is presenting an exhibition focused on “Cellular-care”. The company has been accelerating research on aging prevention and has announced that it has obtained a patent for demonstrating the senescent cell–removing effect of Persian silk tree. In addition to the details of the research that led to the patent, the briefing also covered the story behind “Rice soft candy”, which is being distributed exclusively at the Signature Pavilion “EARTH MART”. This newsletter provides a summary of the press releases announced today. &lt; Summary &gt;① Accelerating Research on Aging Prevention Glico demonstrates senescent cell removal by Persian silk tree and obtains patent —Discovered from Glico’s Library of 6,000 Curated Ingredients —Ezaki Glico Co., Ltd. conducted research to identify ingredients that act on the causes of aging, selecting approximately 6,000 candidates from its curated ingredient library, with a focus on those suitable for food applications. As a result, Glico demonstrated that Persian silk tree removes senescent cells (senolysis*1), and has now obtained a Patent (Patent No. 7659690). This marks the first patent in Japan for the removal of senescent cells using Persian silk tree. Moving forward, the Glico Group will continue its research, including validation in humans, to further explore its potential in aging-related applications. For more information, please visit <a href="https://www.glico.com/global/news/46993/">https://www.glico.com/global/news/46993/</a>.② Each Piece Encapsulates the Gentle Essence of Rice and a Vision for the Future of Our Planet Glico develops “Rice soft candy” using rice-derived ingredients To be distributed exclusively inside “EARTH MART” at Expo 2025 Osaka, Kansai from the End of May<img style="width: 100%;" src="https://imagedelivery.net/H6_s_Eb_ylTWnSEV3HlmYQ/0476051a-49ad-4fea-a976-dcd176492a00/public" alt="Rice flour and rice" /><img style="width: 100%;" src="https://imagedelivery.net/H6_s_Eb_ylTWnSEV3HlmYQ/fe576d3c-0df7-4001-249d-14f3ab059300/public" alt="Rice soft candy" />Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” at Expo 2025 Osaka, Kansai. Under the pavilion’s theme, “Thinking about the lives through eating”, Glico has developed “Rice soft candy” by applying the soft-candy-making technology it has cultivated since its founding—using rice, Japan’s staple food, as the key ingredient. “Rice soft candy” will be offered free of charge to pavilion visitors exclusively within “EARTH MART”, starting from the End of May. The Glico Group will continue to share the value of Japanese food culture with the world and offer new ideas that contribute to “Healthier days, Wellbeing for life”.For more information, please visit <a href="https://www.glico.com/global/news/47011">https://www.glico.com/global/news/47011</a>.&lt; Reference Information &gt;*1 Senolysis: Refers to the selective removal of senescent cells. The term is derived from seno (senescence) and lysis (destruction or breakdown).[Notes of caution]This document is an English translation of the Japanese original. In the event of any differences or inconsistencies between the Japanese and English versions, the Japanese language version shall take precedence.

Marketing / Research

Diet / Health food / Supplement

Food / Sweets

Event

Foreign companies

Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” and a Premium Partner of the “Osaka Healthcare Pavilion” at Expo 2025 Osaka, Kansai. As part of its participation in both pavilions, Glico held a press briefing on April 30 to share two key announcements: a newly obtained patent related to its “Cellular-care” research, and the development of “Rice soft candy” for the Expo 2025. At the “Osaka Healthcare Pavilion”, Glico is presenting an exhibition focused on “Cellular-care”. The company has been accelerating research on aging prevention and has announced that it has obtained a patent for demonstrating the senescent cell–removing effect of Persian silk tree. In addition to the details of the research that led to the patent, the briefing also covered the story behind “Rice soft candy”, which is being distributed exclusively at the Signature Pavilion “EARTH MART”. This newsletter provides a summary of the press releases announced today.

At Expo 2025, Glico Highlights Innovation Through "Cellular-Care" Research and "Rice Soft Candy"

HR / Recruitment

Skin care / Cosmetics / Hair products

Internet service

Film / Drama

Magazines / Books / Publications

Childbirth / Childcare

Interior / Furniture / Storage

Mobile device

Servers / Peripherals

Network / Network Equipment

System / Website / Application development

Electronic components / Semiconductors / Electrical equipment

Department stores / Supermarkets / Convenience stores / Stores

Wholeseller

Manga / Anime

Arcade Game

Toys / Playsets / Dolls

Car / Car Supplies

Motorcycles / Motorcycle Supplies

Daily necessities / Household goods

Garden / DIY

Shoes / Bags

Jewelry / Accessories

Kids / Baby / Maternity

Soft Drinks / Alcoholic drinks

Restaurant / Fast food / Streetfood

Eating at home / Delivery

Fitness / Healthcare

Medical / Hospital

Pharmaceuticals

Pets / Pet Supplies

Gifts / Flowers

Love / Marriage

Funeral

Hotels / inns

Travel / Sightseeing

Theme Park / Amusement park

Residential / Condominium

Commercial facilities / Office buildings

Architecture / Space design

Construction / Civil engineering

Advertising / Promotion / PR

Sales

Management Consulting

Think tank

Legal / Patent / Intellectual Property

Logistics / Warehouse / Cargo

Steel / Metal / Glass / Earth / Stone / Rubber

Chemistry

Electricity / Gas / Resources / Energy

Nature / Weather

School / University

Cram school / Preparatory school / Online education

Life insurance / Non-life insurance

Mobile app

Mobile games

Cooking / Home appliances

Health and Beauty appliances

Application

Ladies' Fashion

Men's Fashion

Accounting

Environment / SGDs / Recycling

International activity

Full time job / Part-time job / Career

E-commerce

Music

Internet Service Provider / Line connection

Camera

AV equipment

Consumer Games

Outdoors / Mountain Climbing

Welfare / Nursing / Rehabilitation

Qualifications / Study Abroad / Language

Childcare / Early childhood education

Banks / Credit unions

Credit card / Loan

Securities / FX / Investment Trusts

Moving

Politics / Government / Local government

Volunteer

Agriculture / Forestry / Fisheries

Bicycle / Bicycle Supplies

Female Related

Venture Capitals

Coaching / Mentoring / Consultation

Automotive / Motorcycle / Bicycle

Automotive / Automotive Supplies

Interior / Goods

Real Estate / Architecture / Construction

Software

Blockchain / Web3

Security

Telecommunications / VoIP

Show Business

Comedy

Food & Beverage

Ezaki Glico Co. Ltd.